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Nick N. Gordon

Sildenafil Citrate

2 min read

Which Medicines Contain Sildenafil?


Hearing the name “Sildenafil citrate”, few will understand the active ingredient of which drug it is. Meanwhile, Sildenafil is the main active substance of Viagra, the most well-known remedy for erectile dysfunction.
Sildenafil citrate belongs to the pharmacological group of PDE-5 inhibitors. It is a means to increase potency, and is also used to treat pulmonary arterial hypertension. Initially, this artificially synthesized substance was intended exactly to reduce the pressure in the vessels of the lungs, and it was only during the clinical trials of Viagra that it turned out that Sildenafil positively affects erection.
Sildenafil-containing medicine for combating is marketed as Revatio. One pill of this medicine contains 20 mg of the active ingredient.
One pill of Viagra contains 25, or 50, or 100 mg of Sildenafil.


Main Contraindications of Sildenafil Citrate

The medicines containing Sildenafil are contraindicated for patients who take nitrates, nitric oxide donors or alpha blockers. Their combination with Sildenafil can cause severe drop in blood pressure.

As for diseases, Sildenafil is contraindicated for persons suffering from arrhythmias, ischemic heart disease and other disorders of the cardiovascular system, veno-occlusive lung disease, ischemic neuropathy of the optic nerve, degenerative hereditary retinal diseases, severe liver dysfunction, severe hypotension and some other pathological conditions. People under 18 years old should not take it either.

What Are Side Effects of Sildenafil?


In both cases of the use of Sildenafil citrate, side effects such as headache, redness of the skin of the face, difficulty falling asleep, nasal congestion, nausea, pain in the back muscles, and color disturbances may be observed. This does not mean that one patient experiences all kinds of side effects simultaneously, usually one or two unpleasant sensations are present.